LifeCell Review

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Editor Rating:
3.1 / 5.0
Rating: 3.1/5.
By: Michelle Green

LifeCell Overview

Reportedly discovered by a plastic surgeon from Columbia University, LifeCell promises to reduce the presence of multiple signs of aging, including fine lines, deep wrinkles, bags under the eyes, crow’s feet and much more. Using the stem cells of a rare strain of Swiss apple, LifeCell proclaims they can protect and rejuvenate the skin indefinitely.

A Closer Look at LifeCell

Although this claim may sound too good to be true, it holds some water, because this product works in two ways: it reflects light to reduce the appearance of wrinkles instantly and combats the causes of wrinkles to reduce them in the long-run. Some results are nearly instant. Upon applying the product, users will see an immediate improvement in the look of wrinkles, as they have been filled and are no longer creating the shadows that the human eye can detect. In that regard, it works absolutely perfectly.

However, the claim that LifeCell can indefinitely rejuvenate the skin is predicated on the user applying the product perpetually. Which means if you want to continue to see results, you must keep buying it and using it. Even though the swiss apple stem cells can do some miraculous things for our skin, they cannot allow our cells to divide beyond the predetermined amount. So, if after a 30-day free trial you decide to continue, then you must pay $189 for the product you have already used, and continue to pay $149 every 60 days for a new order. A bit on the pricy side, but if so many celebrities use it, then surely it works, right?

See the power of plant stem cells in LifeCell.

Well, while it claims to be celebrity endorsed, a closer look at the photos on LifeCell’s website reveals the truth in the small print. Many photos of the product with celebrities have a caption at the bottom reading: “Received LifeCell at award show event. Not an endorsement.” Next to the photos in bold lettering is the claim “TESTED ON CELEBRITIES NOT ANIMALS”. But not the celebrities in the photos, evidently. It’s a clever little trick, but a trick nonetheless, and one that makes reviewers question the credibility of LifeCell.


  • Nourishes and moisturizes skin
  • Reduces the appearance of imperfections and discolorations
  • Gradually eliminates the appearance of dark circles and under-eye puffiness
  • Helps stimulate the production of collagen
  • Not animal tested


  • Costly price tag for the average consumer
  • Some questionable ingredients like Fumed Silica and Silicone Dioxide
  • “Media” reviews are about one particular ingredient, not LifeCell itself
  • Paid reviews can lead to bias

Key Ingredients

There are several ingredients featured within the LifeCell formula that have scientific evidence proving that they can have a positive benefit on your skin. These individual components are popular throughout the beauty industry; many other products on the market contain these same ingredients. These include things like Retinol, D3PA, Argireline, and others, which we take an in-depth look at below. However, there are also less than stellar additives, like Silica and Silicone, which add a nice feel but ultimately aren’t great for the skin.

Dithiolane 3-Pentanic Acid

Also known as D3PA, this is a naturally occurring compound in the human body. When applied externally and topically, it helps to enhance the production of nitric oxide to dilate capillaries and enhance blood flow to your face. It is also an antioxidant, and kills harmful free radicals. Free radicals are one of the largest sources of new wrinkle formations. D3PA also helps reduce puffiness.

Ascorbyl Palmitate

This potent form of Vitamin C is a solution created in a lab to be fat-soluble, meaning it can dissolve and still function in oils, creams, serums, and other products. Because it is derived from Vitamin C but not as harsh as the pure version, it is a great match for those with sensitive skin. It helps to protect skin from harmful UV rays while assisting with making new collagen.

Acetyl Hexapeptide-3

Though it is often called ‘Botox in a Jar’, this topical formula is not a toxin. It is derived from one, however. Namely, botulinum toxin, the scientific name for Botox. The more common market name for this derivative is Argireline. It helps partially inhibit facial muscles from extreme reactions, mimicking its Botox cousin , which will help neutralize the creation of new lines and wrinkles.


This neurotransmitter is also called Deanol, if you aren’t wearing a lab coat. Studies show that it acts as an anti-inflammatory, reducing puffiness in the face and around the eyes. It also helps to mitigate fine lines and wrinkles on the facial skin and forehead. As an added bonus, when taken as a supplement (don’t eat your skin cream) it is thought to increase the production of acetylcholine, a particular type of chemical that helps transmit nerve cells and boosts learning and memory. It also helps firm skin and improves tone over time.

Full List of Ingredients

Water, Caprylic/Capric Triglycerides, Ethoxydiglycol, Stearyl Alcohol, Stearic Acid, Peg-100 Stearate, Glyceryl Stearate, Diisopropyl Dimer Dilinoleate, Magnesium Aluminum Silicate, Peg-40 Stearate, Oxide Reductases, Soy Peptides, Cyclomethicone, Hydrolyzed Rice Bran Extract, Deanol, Dithiolane-3-Pentanoic Acid, Copper Gluconate, Magnesium Aspartate, Zinc Gluconate, Acetyl Hexapeptide-3, Idebenone, Ascorbyl Palmitate, Fumed Silica, Silicone Dioxide, Propylene Glycol, Imidazolidinyl Urea.

Directions: How to Use LifeCell

To make sure your skin is not sensitive to any of the ingredients in LifeCell, it is recommended that a patch test be performed at least 24 hours prior to use. If irritation occurs, discontinue use.
Once daily, apply a small amount of the product to clean, dry skin using your fingertips. You can also apply to lips, skin around the eyes, neck, décolleté, and behind your ears for maximum effectiveness.

The Final Word on LifeCell

While the marketing and website might make some claims that are less than completely truthful, the science seems to stand behind LifeCell. If you can afford the high-end price and are willing to overlook the white lies, it could potentially help with your aging skin, or at least reduce the appearance of wrinkles on a day to day basis.

For information on our top-rated products, see below.


(5.0 / 5.0)
  • #1 recommended to support younger-looking skin.
  • Clinically shown to reduce fine lines and wrinkles.
(4.5 / 5.0)
  • Rescues and protects skin from damage.
  • Deeply moisturizes to reduce fine lines and wrinkles.
(4.0 / 5.0)
  • All-in-one, full spectrum anti-aging serum
  • Repairs and fights damage to keep skin healthy and youthful
(3.8 / 5.0)
  • Contains Ritapro 165, a next-gen moisturizer
  • Helps to reduce the appearance of lines and wrinkles
(3.6 / 5.0)
  • High level hydration that lasts all day
  • Uses Padina pavonica algae to boost collagen.

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